APOE antibody (Agarose Beads)

Catalog No. ABIN7795847

This Goat Polyclonal antibody specifically detects APOE in . It exhibits reactivity toward Human.

Quick Overview for APOE antibody (Agarose Beads) (ABIN7795847)

Target: APOE (Apolipoprotein E (APOE))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This APOE antibody is un-conjugated

Application: Please inquire

Clone: G05

Product Details anti-APOE Antibody

Binding Specificity: Agarose Beads

Purpose: Goat anti-Human ApoE Antibody Agarose Immobilized

Purification: Purified

Immunogen: Human Apolipoprotein E

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5 mg/mL

Buffer: 75 mM PBS, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, 0.1 mM PMSF, pH 7.3

Preservative: Other preservative, PMSF, Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for APOE

Target: APOE (Apolipoprotein E (APOE))

Alternative Name: ApoE

Background: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

Gene ID: 348

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism